
Depo-Provera Side Effects: Brain Tumor Risk Identified
Eligible individuals may receive compensation—check today.
Alarming Findings About Depo-Provera Link It To:
-
Brain tumors
-
Breast cancer
-
Blood clots
-
Osteoporosis
-
Ectopic pregnancy
-
Cervical cancer
Other side effects of Depo-Provera include:
-
​Belly pain, Bloating, Depression, Dizziness, Headaches, Irregular periods, and Weight gain.
What to Do If You’ve Used Depo-Provera
For many women, Depo-Provera offers the freedom of long-term contraception, but concerns about its safety are rising. Studies suggest a potential link between prolonged use and brain tumors like meningioma.
If you’ve experienced health issues after using Depo-Provera, it might be time to consider legal options. Start by gathering your prescription records, medical diagnoses, and treatment documents.
These records can play a crucial role in litigation against the manufacturers of Depo-Provera.
​
Need assistance? Reach out to Bonnie Spencer of The Spencer Law Firm at 713-961-7770 to discuss your case.
About
Understanding Depo-Provera
Legal Implications and Health Considerations
Depo-Provera, a widely used contraceptive injection, has been a reliable option for many women seeking long-term birth control. Manufactured by Pfizer, this injectable form of progestin has been administered to millions globally. However, recent studies have raised concerns about its safety profile, particularly regarding an increased risk of developing brain tumors. This article delves into the legal implications and health considerations associated with Depo-Provera, focusing on developments pertinent to residents of Houston, Texas.


What is Depo-Provera?
Depo-Provera is an injectable contraceptive containing medroxyprogesterone acetate, a synthetic form of the hormone progesterone. Administered every three months, it effectively prevents pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the uterine lining. Its convenience and long-acting nature have made it a popular choice among women seeking reliable birth control.
​
Recent Health Concerns
​
In March 2024, a study published in the British Medical Journal established a significant association between prolonged use of Depo-Provera and an increased risk of developing meningiomas, a type of non-cancerous brain tumor. The research indicated that women who used Depo-Provera for more than a year had a five to six-fold increased risk compared to those who did not use the contraceptive.
Legal Implications
The findings from the aforementioned study have prompted legal actions against Pfizer, the manufacturer of Depo-Provera. As of January 2025, over 20 lawsuits have been filed in the United States by women who developed meningioma brain tumors after using Depo-Provera. These lawsuits allege that Pfizer failed to adequately warn users about the increased risk of developing brain tumors associated with long-term use of the contraceptive.
In Texas, including Houston, residents who have used Depo-Provera and developed meningiomas may have grounds to pursue legal action. The lawsuits claim that Pfizer knew or should have known about the risks but did not provide sufficient warnings to consumers. Legal experts suggest that individuals who have used Depo-Provera for extended periods and have been diagnosed with meningiomas should consult with a qualified attorney to explore their options.


Health Considerations
For women in Houston and across Texas considering or currently using Depo-Provera, it is crucial to be informed about the potential risks. While the overall risk remains relatively low, the association with meningiomas warrants attention. Healthcare providers should discuss these risks with patients, especially those considering long-term use.
​
Alternative contraceptive methods, such as oral contraceptives, intrauterine devices (IUDs), or implants, may offer different risk profiles. Consulting with a healthcare professional can help determine the most appropriate and safe option based on individual health history and preferences.
Conclusion
​
Depo-Provera has been a cornerstone in contraceptive care for many women. However, emerging research highlighting potential health risks, particularly the increased risk of brain tumors, underscores the importance of informed decision-making. Residents of Houston, Texas, should be aware of these developments and consult with healthcare providers to make choices that align with their health needs and personal circumstances.
For those affected by adverse health outcomes related to Depo-Provera, seeking legal counsel is advisable to understand potential recourse and compensation options. Engaging with experienced attorneys can provide guidance through the complexities of pharmaceutical litigation and help ensure that individuals' rights are protected.
How Many Lawsuits have been filed till date in US
As of January 2025, over 20 lawsuits have been filed in the United States by women who developed meningioma brain tumors after using Depo-Provera.
​
These lawsuits allege that Pfizer, the manufacturer of Depo-Provera, failed to adequately warn users about the increased risk of developing brain tumors associated with long-term use of the contraceptive. The first lawsuit was filed in October 2024 by a California woman who used Depo-Provera between 2005 and 2021 and was diagnosed with a meningioma at the age of 37.
​
Given the growing number of cases, the U.S. Judicial Panel on Multidistrict Litigation (JPML) is considering consolidating these lawsuits into a multidistrict litigation (MDL) to streamline the legal process. A hearing is scheduled for January 30, 2025, in Miami, Florida, to discuss this consolidation.

Depo-Provera Side Effects
Depo-Provera, a contraceptive injection containing the hormone progestin, is associated with several side effects that individuals commonly inquire about:
​
-
Irregular Menstrual Bleeding: Users may experience changes in their menstrual cycles, including irregular periods, spotting, or, in some cases, cessation of menstruation.
-
Weight Changes: Some individuals report weight gain or loss while using Depo-Provera. Maintaining a balanced diet and regular exercise can help manage these changes.
-
Headaches and Dizziness: Headaches and feelings of dizziness have been noted as potential side effects. If these symptoms persist or are severe, consulting a healthcare provider is advisable.
-
Mood Changes: Some users experience mood swings, nervousness, or depression. It's important to monitor any significant changes in mood and seek medical advice if necessary.
-
Decreased Bone Mineral Density: Long-term use of Depo-Provera has been linked to a reduction in bone mineral density, which may increase the risk of osteoporosis and fractures later in life. This risk is particularly concerning for adolescents and young adults.
-
Delayed Return to Fertility: After discontinuing Depo-Provera, there may be a delay in the return to fertility, with some individuals taking up to 10 months or more to begin ovulating again.
-
Potential Link to Brain Tumors: Recent studies have suggested a possible association between long-term use of Depo-Provera and an increased risk of developing intracranial meningioma, a typically non-cancerous brain tumor. Legal actions are being considered in some countries based on these findings.
It's crucial to discuss these potential side effects with a healthcare provider to determine if Depo-Provera is the appropriate contraceptive method based on individual health profiles and needs.
There have been legal actions concerning Depo-Provera, particularly focusing on its potential link to brain tumors. A significant study published in the British Medical Journal in March 2024 found that women who used Depo-Provera for more than a year had a five-to-six-fold increased risk of developing intracranial meningiomas, a type of non-malignant brain tumor, compared to non-users.
​
Following this study, numerous lawsuits have been filed against Pfizer, the manufacturer of Depo-Provera. Plaintiffs allege that Pfizer failed to adequately warn users about the increased risk of developing brain tumors associated with long-term use of the contraceptive. These legal actions are based on claims that Pfizer knew or should have known about the potential risks but did not disclose them appropriately.
​
In the United States, the Judicial Panel on Multidistrict Litigation (JPML) is considering centralizing the growing number of lawsuits under MDL No. 314. A hearing is scheduled for January 30, 2025, in Miami, Florida, to determine the consolidation of these cases. Pfizer has indicated agreement on the need for an MDL to manage the increasing number of Depo-Provera lawsuits.
​
Internationally, similar legal actions are emerging. In Australia, Shine Lawyers is investigating potential class-action lawsuits against Pfizer, encouraging users of Depo-Provera who have developed brain tumors to come forward. This follows the findings of the French study linking long-term use of Depo-Provera to an increased risk of intracranial meningiomas.
​
These developments indicate a growing legal response to concerns about the safety of Depo-Provera, particularly regarding its association with brain tumors.
In the United States, there have been significant legal developments concerning Depo-Provera, particularly regarding its potential link to brain tumors. As of January 2025, over 20 lawsuits have been filed by women who developed meningioma brain tumors after using Depo-Provera. These plaintiffs allege that Pfizer, the manufacturer, failed to adequately warn users about the increased risk of developing brain tumors associated with long-term use of the contraceptive.
​
In response to the growing number of cases, the U.S. Judicial Panel on Multidistrict Litigation (JPML) is scheduled to hear arguments on January 30, 2025, in Miami, Florida, regarding the consolidation of these lawsuits into a multidistrict litigation (MDL). Both plaintiffs and Pfizer have expressed support for the creation of an MDL to efficiently manage the litigation process.
​
Despite the mounting legal actions and studies indicating a potential link between Depo-Provera and brain tumors, Pfizer has not yet updated the warning labels in the U.S. to reflect these risks. The company maintains that Depo-Provera has been a safe and effective contraceptive option for millions of women over the past 30 years and intends to vigorously defend against these lawsuits.
​
These developments highlight the ongoing legal scrutiny of Depo-Provera in the United States, focusing on the alleged failure to disclose serious health risks associated with its long-term use.
Could Depo-Provera Increase Brain Tumor Risks? Experts Weigh In
A few studies have examined the long-term effects of synthetic progestins, such as medroxyprogesterone acetate, and have raised concerns about their role in promoting tumor growth specifically meningioma (tumors that develop in the outer layers of tissue between the brain and skull). Some members of the medical community have raised concerns about the long-term use of high dose hormonal contraceptives and their potential risks.
Medroxyprogesterone acetate, the active ingredient in Depo-Provera, is a synthetic form of the hormone progesterone. Some believe that synthetic hormones may have different effects on the body compared to naturally occurring hormones, which could potentially contribute to the development of certain cancers. Furthermore, since Depo-Provera is typically used for extended periods (often for many years), some experts worry about the cumulative effects of medroxyprogesterone acetate on brain tissue and whether prolonged exposure might increase the risk of developing brain tumors.
What Should you do?
If you are concerned about the potential risks of Depo-Provera, it’s important to have a conversation with your healthcare provider. They can help assess your individual risk factors, provide guidance based on your health history, and discuss alternative contraception methods that might be better suited to your needs.
Potential Litigation
If you have long term exposure to Depo-Provera and have developed meningioma you may need to consider joining the growing number of women who have filed suit against the manufacturers of Depo-Provera.
Even if you have yet to suffer any injuries, it is extremely important that you gather your prescription and medical records related to the injections you received. If you have suffered injuries as a result of these injections you will want to gather any records reflecting the diagnosis and any treatments for injuries you may have suffered.
​
For many women, Depo-Provera offers the freedom of long-term contraception, but concerns about its safety are rising. Studies suggest a potential link between prolonged use and brain tumors like meningioma.
If you’ve experienced health issues after using Depo-Provera, it might be time to consider legal options. Start by gathering your prescription records, medical diagnoses, and treatment documents. These records can play a crucial role in litigation against the manufacturers of Depo-Provera.
​
​
Need assistance? Reach out to Bonnie Spencer of The Spencer Law Firm at 713-961-7770 to discuss your case.
​
How to File a Depo Provera Lawsuit
Step-by-Step Guide
Depo Provera Settlements in 2025
As we move closer to 2025, discussions around Depo Provera settlements have gained significant traction.
These conversations are vital as they speak to the health and safety of many women. Understanding the potential outcomes of these settlements is essential not only for patients but also for healthcare providers and the pharmaceutical industry as a whole.
Implications for Pharmaceutical Litigation
If settlements occur, we could see stricter regulations about how pharmaceutical companies disclose risks and advertise their products. Lawmakers may respond by enacting changes that ensure patients receive clear information about potential side effects.
Such regulations may extend beyond Depo Provera, influencing marketing strategies for various medications. Striving for greater safety measures could lead to improved health outcomes for consumers, a goal that aligns with public health initiatives.
Financial Implications for Stakeholders
The financial repercussions of these settlements could be extensive. For affected patients, compensation could alleviate the severe financial burdens of medical bills and lost wages. For instance, estimating costs related to osteoporosis treatment can exceed $9,000 annually for some individuals. This financial relief could also enhance their overall quality of life.
On the flip side, the pharmaceutical company may face significant settlements, affecting their financial stability. In 2022, similar legal battles resulted in settlements totaling over $1 billion for other pharmaceutical companies, illustrating the potential scale of financial penalties that could reshape market dynamics.
Stakeholders must stay informed
The unfolding discussion around Depo Provera settlements is complex and multifaceted. From financial implications for patients and pharmaceutical companies to shifts in societal attitudes about women’s health, the outcomes of these settlements will undoubtedly influence conversations for years to come.
Stakeholders must stay informed and engaged as we head into 2025. Advocating for necessary changes will be critical in ensuring that all women have access to safe, effective, and clearly communicated contraceptive options. The journey toward transparency and improved health outcomes is a shared responsibility, and as we navigate this landscape, we must keep the focus firmly on women’s health.
Depo Provera, a popular birth control injection, has been linked to severe side effects, including bone density loss, blood clots, and other health complications. If you or a loved one have suffered harm due to Depo Provera, you may be eligible to file a lawsuit against the manufacturer. This guide will walk you through the step-by-step process of filing a Depo Provera lawsuit, helping you understand your legal options and how to pursue compensation for your damages.
Step 1: Determine If You Have a Case
Before filing a lawsuit, it is essential to determine whether you have a valid legal claim. You may have grounds for a lawsuit if:
​
-
You have suffered serious side effects such as osteoporosis, bone fractures, blood clots, or other severe health complications.
-
You were not adequately warned about the risks associated with Depo Provera.
-
There is evidence that the manufacturer, Pfizer, failed to disclose critical safety information.
If you believe you meet these criteria, consulting with a legal professional is the next step.
Step 2: Gather Medical Records and Evidence
To build a strong case, you need comprehensive documentation of your medical history and treatment. Collect:
​
-
Medical records showing your Depo Provera injections and subsequent health issues.
-
Doctor’s notes explain the link between Depo Provera and your medical condition.
-
Pharmacy records confirming your prescription history.
-
Personal journal entries documenting symptoms and how they have affected your daily life.
Having strong evidence will help prove that Depo Provera caused your injuries.
Step 3: Consult a Depo Provera Lawsuit Attorney
Mass tort and pharmaceutical injury cases are complex, requiring the expertise of a seasoned attorney. Choose a law firm that specializes in defective drug lawsuits and has experience handling cases against large pharmaceutical companies. Your attorney will:
​
-
Evaluate your case and determine the best legal strategy.
-
Help you understand your legal rights and options.
-
Represent you in negotiations and court proceedings.
A lawyer will work on a contingency fee basis, meaning you won’t pay unless you win your case.
Step 4: File a Claim and Join a Mass Tort Lawsuit (If Applicable)
​
Your attorney will file a legal complaint against Pfizer, the manufacturer of Depo Provera. Depending on your case, you may:
​
-
File an individual lawsuit if your circumstances are unique.
-
Join a mass tort lawsuit where multiple plaintiffs with similar injuries sue the same defendant.
-
Become part of a class-action lawsuit if one exists for Depo Provera victims.
Your lawyer will help determine the best course of action based on your specific case.
Step 5: Engage in the Discovery Process
Once the lawsuit is filed, the discovery phase begins. This is where both sides gather and exchange evidence, including:
​
-
Medical expert testimonies.
-
Internal documents from Pfizer regarding Depo Provera’s safety.
-
Depositions from medical professionals and company representatives.
Your legal team will work to strengthen your case by proving the connection between Depo Provera and your injuries.
Step 6: Settlement Negotiations or Trial
Most pharmaceutical lawsuits are resolved through settlements, where the defendant agrees to pay compensation without going to trial. Your attorney will negotiate to get the highest possible settlement for:
​
-
Medical expenses (past and future).
-
Lost wages and reduced earning capacity.
-
Pain and suffering.
-
Other related damages.
If a fair settlement is not reached, your case may proceed to trial, where a judge or jury will decide the outcome.
Step 7: Receive Compensation
If your case is successful, you will receive compensation for your injuries. The amount depends on:
​
-
The severity of your injuries.
-
The impact on your quality of life.
-
The strength of the evidence presented.
Your attorney will ensure you receive the funds as soon as possible so you can cover medical expenses and other losses.
Why Choose The Spencer Law Firm for Your Depo Provera Lawsuit?
​
At The Spencer Law Firm, we specialize in holding pharmaceutical companies accountable for the harm they cause. Our experienced attorneys are dedicated to fighting for victims of defective drugs, ensuring they receive the justice they deserve.
​
Contact us today for a free consultation and let us help you take the first step toward compensation.
​
Final Thoughts
Filing a Depo Provera lawsuit can be a complex and challenging process, but with the right legal team, you can fight for your rights and seek compensation for the harm you’ve suffered. By following these steps and working with an experienced attorney, you increase your chances of a successful outcome.
​
If you believe you have a case, don’t wait—reach out to The Spencer Law Firm's Depo Provera lawsuit attorney today. (713)-961-7770
